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Cytoskeleton 超值大促,助力小 G 蛋白研究!

发布者:艾美捷科技发布时间:2019-03-10

 

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常闻三月之春光秀丽兮,
 
万物始以惊蛰;
 
故特推 Cytoskeleton 之促销兮,
 
回馈以尊敬之顾客。
 
即日至谷雨兮,
 
巧推超值产品以示诚意也 ;
 
艾美捷设巨惠小 G 蛋白产品线以大促兮,
 
折扣包您满意也。
 
吾不多言语 Cytoskeleton 众多大促产品兮,
 
请您阅具体下文也。
 

 

        为答谢和回馈广大科研工作者们长期以来对武汉艾美捷科技有限公司的大力支持,艾美捷科技联合细胞骨架领域顶级供应商 Cytoskeleton 联合推出:小 G 蛋白产品线超值大促,一年仅此一次,千万不要错过啊!本次促销活动产品涵盖 GEFs, 小 G 蛋白G-LISA 活化试剂盒等。

 

        小 G 蛋白(Small G Protein)因分子量只有 20—30KD 而得名,同时具有 GTP 酶活性,在细胞信号通路中发挥分子开关的功能,参与调控很多生物学过程,包括分泌活动和细胞骨架的装配等。目前发现的小 G 蛋白包括 Rho, Rac, Arf1 & 6, Ras, Ral 等。小 G 蛋白的共同特点是,当结合了 GTP 时即成为活化形式,这时可作用于下游分子使之活化,而当 GTP 水解成为 GDP 时(自身为 GTP 酶)则恢复到非活化状态。

 

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        Pull-down 和 G-LISA 实验都被广泛地用于研究小 G 蛋白的活性。Pull-down 实验又叫蛋白质体外结合实验,可用于测定活性的 GTPase 亚型,可作为对 G-LISA 实验的补充。G-LISA 实验是一种改进的 ELISA,可测定 3-D 细胞系、原代细胞裂解液及组织裂解液中有 活性的 GTPase,使 GTPase 定量的准确性增加。

 

活动详情:
 
时间:即日起-2020 年 4 月 22 日
对象:仅限中国区终端客户
品目:GEFs, 小 G 蛋白和 G-LISA 活化试剂盒等产品(详情见下方活动品目列表)
内容: 直享 6.5 折超低优惠!
 
活动品目列表:

 

货号

产品名称

规格

目录价

促销价

ACD03

Anti-Cdc42 Mouse Monoclonal Antibody

2x200ul

5590

3634

ACD03-S

Anti-Cdc42 Mouse Monoclonal Antibody (sample size)

1x50ul

1572

1022

ARC03

Anti-Rac1 specific mouse MAb

2x100ul

5590

3634

ARC03-S

Anti-Rac1 specific mouse MAb(sample size)

1x25ul

1572

1022

ARH05

Anti-RhoA antibody (mouse MAb) + control.

2x200ul

5590

3634

ARH05-S

Anti-RhoA antibody (mouse MAb) + control.  (Trial size)

1x50ul

1572

1022

BK008

Ras Activation Assay Biochem Kit

KIT50assays

11326

7362

BK008-S

Ras Activation Assay Biochem Kit

KIT20assays

5752

3739

BK030

Combo RhoA/Rac1/Cdc42 Activation Assay Kit

KIT3x10assays

14988

9742

BK032-S

Arf1 Pulldown Activation Assay Kit

KIT20assays

6886

4476

BK033-S

Arf6 Pulldown Activation Assay Kit

KIT20assays

6886

4476

BK034

Cdc42 Pulldown Activation Assay Kit

KIT50assays

11326

7362

BK034-S

Cdc42 Pulldown Activation Assay Kit

KIT20assays

5752

3739

BK035

Rac1 Pulldown Activation Assay Kit

KIT50assays

11326

7362

BK035-S

Rac1 Pulldown Activation Assay Kit

KIT20assays

5752

3739

BK036

RhoA Pulldown Activation Assay Kit

KIT80assays

11326

7362

BK036-S

RhoA Pulldown Activation Assay Kit

KIT20assays

5752

3739

BK040

RalA Activation Assay Biochem Kit

KIT50assays

11326

7362

BK100

GEF Exchange Assay

KIT60-300assays

10451

6793

BK105

GAP Assay Kit

KIT80-160assays

10451

6793

BK121

RhoA G-LISA Activation Assay (luminescence)

KIT96assays

14097

9163

BK124

RhoA G-LISA Activation Assay (absorbance)

KIT96assays

14097

9163

BK124-S

RhoA G-LISA Activation Assay (absorbance)

KIT24assays

8507

5529

BK125

Rac1,2,3 G-LISA Activation Assay Kit

KIT96assays

14097

9163

BK126

Rac1 G-LISA Activation Assay Kit

KIT96assays

14097

9163

BK127

Cdc42 G-LISA Activation Assay Kit

KIT96assays

14097

9163

BK127-S

Cdc42 G-LISA Activation Assay Kit

KIT24assays

8507

5529

BK128

Rac1 G-LISA Activation Assay Kit

KIT96assays

14097

9163

BK128-S

Rac1 G-LISA Activation Assay Kit

KIT24assays

8507

5529

BK129

RalA G-LISA Activation Assay Kit

KIT96assays

14097

9163

BK131

Ras G-LISA Activation Assay Kit

KIT96assays

14097

9163

BK132

Arf1 G-LISA Activation Assay Kit

KIT96assays

14097

9163

BK133

Arf6 G-LISA Activation Assay Kit

KIT96assays

14097

9163

BK135

G-LISA Bundle (BK135 = BK124-S + BK127-S + BK128-S)

3KITS(24assays/kit)

23495

15272

BK150

RhoA ELISA Kit

KIT96assays

7697

5003

C17G01-A

Cdc42-GST protein: dominant negative

1x25ug

4213

2738

C6101-A

Cdc42-His Protein: constituitively active

1x10ug

4213

2738

CD01-A

Cdc42-His Protein: Wild type

1x100ug

4213

2738

CD01-C

Cdc42-His Protein: Wild type

3x100ug

10289

6688

CD01-XL

Cdc42-His Protein: Wild type

1x1mg

21874

14218

CDG01-C

Cdc42-GST Protein: Wild type

8x25ug

7859

5108

CN01-A

Rho Activator

5x10units

3224

2096

CN01-B

Rho Activator

20x10units

11747

7636

CN02-A

Rac and Cdc42 Activator

5x10units

3224

2096

CN02-B

Rac and Cdc42 Activator

20x10units

11747

7636

CN03-A

Rho activator II

3x20ug

3224

2096

CN03-B

Rho activator II

9x20ug

9074

5898

CN04-A

Rho/Rac/Cdc42 Activator I

3x20ug

3224

2096

CN04-B

Rho/Rac/Cdc42 Activator I

9x20ug

9074

5898

CS-GE03

Ras-GRF GEF protein (human recomb. CDC25 domain, MBP tagged)

1x100ug

5590

3634

CS-GE04

Tiam1 GEF protein (human recomb. DHPH domain, MBP tagged)

1x100ug

5590

3634

CS-GE05

Vav1 GEF protein (human recomb. DHPHC1 domain Y174D mutant, 6xHis tagged)

1x100ug

5590

3634

CS-GE06

Vav2 GEF protein (human recomb. DH domain, 6xHis tagged)

1x100ug

5590

3634

CS-GE07

ARNO Protein: GEF (Sec7) domain (aa31- 267, human recomb., 6xHis tagged)

1x100ug

5590

3634

CS-GE08

SOS2 exchange domain (563-1051) protein (Human recombinant)

1x100ug

5590

3634

CS-GE09

RAPGEF5 Protein: Ras association and exchange domain (57– 580) wild type. (Human recombinant, GST tagged)

1x100ug

5590

3634

CS-RS02

N-Ras Protein; wild-type (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS03

K-Ras4B Protein: wild-type (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS04

K-Ras4B Mutant Protein: G12V (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS05

R-Ras Protein: wild-type (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS06

K-Ras4B Mutant Protein: G13D (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS07

K-Ras4B Mutant Protein: G13S (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS08

K-Ras4B Mutant Protein: K128A (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS09

K-Ras4B Mutant Protein: Q61P (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS10

K-Ras4B Mutant Protein: R135A (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS11

K-Ras4B Mutant Protein: G12D+I36N (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS12

K-Ras4B Mutant Protein: G12D+D38A (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CS-RS13

K-Ras4B Mutant Protein: G12D (human recombinant with 6xHis-tag)

1x100ug

6238

4055

CT03-A

C3 transferase protein

1x25ug

3224

2096

CT03-C

C3 transferase protein

4x25ug

11261

7320

CT04-A

Cell Permeable Rho Inhibitor (C3 Trans based))

1x20ug

3224

2096

CT04-B

Cell Permeable Rho Inhibitor (C3 Trans based))

5x20ug

9641

6267

CT04-C

Cell Permeable Rho Inhibitor (C3 Trans based))

20x20ug

25520

16588

GAP01-A

Rho GAP Protein GST

1x50ug

4456

2896

GAP01-B

Rho GAP Protein GST

4x50ug

10937

7109

GAS01-A

Rho GAP Protein: catalytic domain GST

1x50ug

4456

2896

GAS01-B

Rho GAP Protein: catalytic domain GST

4x50ug

10937

7109

GDI01-A

GDP dissociation inhibitor protein GST fusion

1x25ug

4456

2896

GE01-A

Dbs protein GEF domain - HIS fusion

2x50ug

4456

2896

GE02

SOS1 Ras GEF protein (human recomb. ExD domain, 6xHis tagged)

1x100ug

5266

3423

GE02-XL

SOS1 Ras GEF protein (human recomb. ExD domain, 6xHis tagged)

1x1mg

26735

17378

GGA07-A

GGA3-PBD Arf Affinity Beads

1x500ug

6886

4476

PAK01-A

PAK Rac1/Cdc42 binding domain protein

1x250ug

6076

3950

PAK01-B

PAK Rac1/Cdc42 binding domain protein

4x250ug

16122

10479

PAK02-A

PAK Beads, Rac1/Cdc42 binding domain protein on beads

1x500ug

7048

4581

PAK02-B

PAK Beads, Rac1/Cdc42 binding domain protein on beads

4x500ug

21550

14008

R17G01-A

Rac1 GST Protein: dominant negative

1x25ug

4213

2738

R6101-A

Rac1 His Protein: constitutively active

1x10ug

4213

2738

R6301-A

RhoA His Protein: constitutively active

1x10ug

4213

2738

RC01-A

Rac1 His Protein: wild type

1x100ug

4618

3002

RC01-C

Rac1 His Protein: wild type

3x100ug

10937

7109

RC01-XL

Rac1 His Protein: wild type

1x1mg

21874

14218

RC02-A

Rac2 His Protein: wild type

1x100ug

4618

3002

RCG01-C

Rac1 GST Protein: wild type

8x25ug

7859

5108

RF02-A

Raf protein ras binding domain on GST beads

1x2mg

7534

4897

RF02-B

Raf protein ras binding domain on GST beads

4x2mg

21874

14218

RH01-A

RhoA His Protein: wild type

1x100ug

4618

3002

RH01-C

RhoA His Protein: wild type

3x100ug

10937

7109

RH01-XL

RhoA His Protein: wild type

1x1mg

21874

14218

RH03-A

RhoC His Protein: wild type

1x100ug

4618

3002

RHG01-C

RhoA GST Protein: wild type

8x25ug

7859

5108

RR02-A

Rap1b protein (Human wild type, His)

1x100ug

4618

3002

RS01-A

H-Ras Protein; wild type 6xHis Tag

1x100ug

4618

3002

RS01-C

H-Ras Protein; wild type 6xHis Tag

3x100ug

10937

7109

RT01-A

Rhotekin RBD protein GST fusion

1x500ug

6886

4476

RT02-A

Rhotekin RBD protein on GST beads

2x2mg

9155

5951

RT02-B

Rhotekin RBD protein on GST beads

6x2mg

21874

14218

VCG03-A

VCA domain of WASP (GST fusion)

1x500ug

7697

5003

 

* 本活动最终解释权归艾美捷科技所有

 

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